Fecal microbiota transplant for Clostridium difficile infection in older adults

Clostridium difficile Infection and Fecal Microbiota Transplant.

Clostridium difficile infection (CDI) is a major source of morbidity and mortality for hospitalized patients. Although most patients have a clinical response to existing antimicrobial therapies, recurrent infection develops in up to 30% of patients. Fecal microbiota transplant is a novel approach to this complex problem, with an efficacy rate of nearly 90% in the setting of multiple recurrent C...

Fecal microbiota transplant protocol for clostridium difficile infection.

Fecal microbiota transplant has become more acceptable as a therapeutic for recurrent Clostridium difficile infection. The FDA has an enforcement discretion policy for practitioner's performing this therapy, which includes informed consent for this experimental treatment. This manuscript describes a typical procedure that can be followed that includes the important aspects of this preparation a...

Weight Changes in Fecal Microbiota Transplant for Clostridium difficile

Fecal microbiota transplant to treat recurrent Clostridium difficile infections.

The prevalence of recurrent or refractory Clostridium difficile infection has been steadily increasing since 2000. Consequently, alternative treatments to the standard antibiotic therapies are now being considered. One alternative treatment is fecal microbiota transplant. Although fecal microbiota transplant is relatively new--and not appealing to most people--it has been around for many years ...

1798Oral, Frozen Fecal Microbiota Capsules for Relapsing Clostridium difficile Infection

1798. Oral, Frozen Fecal Microbiota Capsules for Relapsing Clostridium difficile Infection Ilan Youngster, MD; George Russell, MD; Christina Pindar,; Jenny Sauk, MD; Elizabeth Hohmann, MD; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Division of Infectious Diseases, Boston Children’s Hospital, Boston, MA...